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Invasive Group B Streptococcal Disease (group B strep, GBS)

DISEASE NAME:

Invasive Group B Streptococcal Disease (group B strep, GBS)

CATEGORY:

Invasive Group B Streptococcal Disease (group B strep, GBS)

Group B Streptococcus (GBS) is a bacteria commonly found in the gut or genital tract (vagina). GBS can occasionally cause serious infections in vulnerable people, in particular newborn babies.

Invasive GBS (iGBS) is an infection where the bacteria is isolated or detected from a normally sterile body site, such as blood or spinal fluid.

iGBS disease in infants under 90 days is a notifiable disease in Ireland.

Guidance

Guidelines for the early clinical and public health management of bacterial meningitis (including meningococcal disease) [Revised November 2016]

File Size: (2MB)
Publication Date: November 2016
Correction. Page 75 - removal of statement stating ciprofloxacin restrictions for certain age groups - Ciprofloxacin can be used in all age groups, as stated in text.  

Case definition

Clinical description
Only group B streptococci (invasive) in infants <90 days old or stillborn infants is notifiable.
In neonates two syndromes exist:
- Early-onset (<7 days old)
- Late-onset (7-89 days old)
Both include sepsis, pneumonia and meningitis.
Stillbirth associated with isolation/detection of Streptococcus agalactiae from the placenta or amniotic fluid is notifiable.

Laboratory criteria
At least one of the following four:
- Isolation of S. agalactiae from a normally sterile site
- Detection S. agalactiae nucleic acid from a normally sterile site
- Isolation of S. agalactiae from the placenta and/or amniotic fluid, with foetal demise
- Detection of S. agalactiae nucleic acid from the placenta and/or amniotic fluid, with foetal demise

Epidemiological criteria
NA

Case classification
A. Possible case
NA
B. Probable case
NA
C. Confirmed case
Any infant or stillborn infant meeting the laboratory criteria

Current as of: 28 May 2018